Pneumocystis jiroveci pneumonie (PJP/PCP)
Advices
| Priority | Medication | Remarks |
|---|---|---|
|
Priority: 1st choice |
Medication: cotrimoxazol (trimethoprim +sulfamethoxazol) iv 1920mg 3dd 3dd 14 to 21 days or
cotrimoxazol (trimethoprim +sulfamethoxazol) po 1920 3dd 14 to 21 days |
Remarks:
+ prednison volgens schema milde gevallen evt. per os |
| Priority | Medication | Remarks |
|---|---|---|
|
Priority: 1st choice |
Medication: dapsone po 100mg 1dd 1dd 21 days +
trimethoprim po 300mg 21 days |
Remarks:
+ prednison volgens schema |
|
Priority: 2nd choice |
Medication: clindamycine 600mg 3dd 3dd 21 days +
primaquine po 30mg 21 days |
Remarks:
+ prednison volgens schema |
|
Priority: 2nd choice alternative |
Medication: atovaquon po 750mg 2dd 2dd 21 days +
primaquine po 30mg 1dd 1dd 21 days |
Remarks:
+ prednison volgens schema Atovaquon suspensie, innemen met voedsel Atovaquon monotherapie evt alleen bij niet-ernstige PJP |
Sources
Antimicrobial resources
The following antimicrobial agents have been used in these recommendations:
- cotrimoxazol (trimethoprim +sulfamethoxazol)
- dapsone
- trimethoprim
- atovaquon
- primaquine
- clindamycine
External antimicrobial resources
Menu position
Metadata
Swab vid: G-499701.2
Updated: 01/02/2021 - 15:25
Status: Published
General comments
Bij pO2 < 8 kPa (70 mmHg) antibiotica i.v. geven en prednison volgens schema:
- Dag 1-5: 2 dd 40 mg
- Dag 6-10: 2 dd 20 mg
- Dag 11-14: 1 dd 20 mg
Secundaire profylaxe: co-trimoxazol 1 dd 480 mg of dapson 1 dd 100 mg of pentamidine vernevelen 1x/maand 300 mg