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Aspergillose - invasief, bekende azol-gevoeligheid

Advices

≥ 18 years

Indications: Invasieve aspergillose (proven

Priority Medication Remarks
Priority:
1st choice
Medication:

voriconazol iv 6mg/kg 2 doses

followed by

voriconazol iv 4mg/kg 2dd

Remarks:

Azol gevoelig

Priority:
1st choice
Medication:

amfotericine B liposomaal (Ambisome) iv 3mg/kg 1dd

Remarks:

Azol resistent of therapie falen op azol

Bij cerebrale lokalisatie dosering verhogen naar 10 mg/kg, 1dd

Priority:
1st choice alternative
Medication:

voriconazol po 400mg 2 doses

followed by

voriconazol po 200mg 2dd

Remarks:

Azol gevoelig

General comments

Zie ook hoofdstuk Aspergillose - invasief, onbekende azol gevoeligheid

Sources

Antimicrobial resources

The following antimicrobial agents have been used in these recommendations:

  • voriconazol
  • amfotericine B liposomaal (Ambisome)
External antimicrobial resources
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Metadata

Swab vid: G-502723.3
Updated: 07/10/2025 - 17:00
Status: Published